PlantImRecepV1, Main, Exploration, bibRecord, 000037

The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.

Identifieur interne : 000037 ( Main/Exploration ); précédent : 000036; suivant : 000038

The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.

Auteurs : Maria A. Schlöffel [Allemagne] ; Andrea Salzer [Allemagne] ; Wei-Lin Wan [Allemagne] ; Ringo Van Wijk [Pays-Bas] ; Raffaele Del Corvo [Allemagne] ; Maja Šemanjski [Allemagne] ; Efthymia Symeonidi [Allemagne] ; Peter Slaby [Allemagne] ; Joachim Kilian [Allemagne] ; Boris Ma Ek [Allemagne] ; Teun Munnik [Pays-Bas] ; Andrea A. Gust [Allemagne]

Source :

Plant physiology [ 1532-2548 ] ; 2020.

RBID : pubmed:32152212

Abstract

Plants have evolved effective strategies to defend themselves against pathogen invasion. Starting from the plasma membrane with the recognition of microbe-associated molecular patterns (MAMPs) via pattern recognition receptors, internal cellular signaling pathways are induced to ultimately fend off the attack. Phospholipase D (PLD) hydrolyzes membrane phospholipids to produce phosphatidic acid (PA), which has been proposed to play a second messenger role in immunity. The Arabidopsis (Arabidopsis thaliana) PLD family consists of 12 members, and for some of these, a specific function in resistance toward a subset of pathogens has been shown. We demonstrate here that Arabidopsis PLDγ1, but not its close homologs PLDγ2 and PLDγ3, is specifically involved in plant immunity. Genetic inactivation of PLDγ1 resulted in increased resistance toward the virulent bacterium Pseudomonas syringae pv. tomato DC3000 and the necrotrophic fungus Botrytis cinerea As pldγ1 mutant plants responded with elevated levels of reactive oxygen species to MAMP treatment, a negative regulatory function for this PLD isoform is proposed. Importantly, PA levels in pldγ1 mutants were not affected compared to stressed wild-type plants, suggesting that alterations in PA levels are not likely the cause for the enhanced immunity in the pldγ1 line. Instead, the plasma-membrane-attached PLDγ1 protein colocalized and associated with the BAK1-INTERACTING RECEPTOR-LIKE KINASES BIR2 and BIR3, which are known negative regulators of pattern-triggered immunity. Moreover, complex formation of PLDγ1 and BIR2 was further promoted upon MAMP treatment. Hence, we propose that PLDγ1 acts as a negative regulator of plant immune responses in complex with immunity-related proteins BIR2 and BIR3.

DOI: 10.1104/pp.19.01292
PubMed: 32152212
PubMed Central: PMC7210654

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000195
to stream Main, to step Curation: 000195

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.</title>
<author><name sortKey="Schloffel, Maria A" sort="Schloffel, Maria A" uniqKey="Schloffel M" first="Maria A" last="Schlöffel">Maria A. Schlöffel</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Salzer, Andrea" sort="Salzer, Andrea" uniqKey="Salzer A" first="Andrea" last="Salzer">Andrea Salzer</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wan, Wei Lin" sort="Wan, Wei Lin" uniqKey="Wan W" first="Wei-Lin" last="Wan">Wei-Lin Wan</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Wijk, Ringo" sort="Van Wijk, Ringo" uniqKey="Van Wijk R" first="Ringo" last="Van Wijk">Ringo Van Wijk</name>
<affiliation wicri:level="4"><nlm:affiliation>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam</wicri:regionArea>
<orgName type="university">Université d'Amsterdam</orgName>
<placeName><settlement type="city">Amsterdam</settlement>
<region>Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Del Corvo, Raffaele" sort="Del Corvo, Raffaele" uniqKey="Del Corvo R" first="Raffaele" last="Del Corvo">Raffaele Del Corvo</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Semanjski, Maja" sort="Semanjski, Maja" uniqKey="Semanjski M" first="Maja" last="Šemanjski">Maja Šemanjski</name>
<affiliation wicri:level="3"><nlm:affiliation>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Symeonidi, Efthymia" sort="Symeonidi, Efthymia" uniqKey="Symeonidi E" first="Efthymia" last="Symeonidi">Efthymia Symeonidi</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Slaby, Peter" sort="Slaby, Peter" uniqKey="Slaby P" first="Peter" last="Slaby">Peter Slaby</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kilian, Joachim" sort="Kilian, Joachim" uniqKey="Kilian J" first="Joachim" last="Kilian">Joachim Kilian</name>
<affiliation wicri:level="3"><nlm:affiliation>Analytics Unit, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Analytics Unit, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ma Ek, Boris" sort="Ma Ek, Boris" uniqKey="Ma Ek B" first="Boris" last="Ma Ek">Boris Ma Ek</name>
<affiliation wicri:level="3"><nlm:affiliation>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Munnik, Teun" sort="Munnik, Teun" uniqKey="Munnik T" first="Teun" last="Munnik">Teun Munnik</name>
<affiliation wicri:level="4"><nlm:affiliation>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam</wicri:regionArea>
<orgName type="university">Université d'Amsterdam</orgName>
<placeName><settlement type="city">Amsterdam</settlement>
<region>Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gust, Andrea A" sort="Gust, Andrea A" uniqKey="Gust A" first="Andrea A" last="Gust">Andrea A. Gust</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany andrea.gust@zmbp.uni-tuebingen.de.</nlm:affiliation>
<country wicri:rule="url">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32152212</idno>
<idno type="pmid">32152212</idno>
<idno type="doi">10.1104/pp.19.01292</idno>
<idno type="pmc">PMC7210654</idno>
<idno type="wicri:Area/Main/Corpus">000195</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000195</idno>
<idno type="wicri:Area/Main/Curation">000195</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000195</idno>
<idno type="wicri:Area/Main/Exploration">000195</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.</title>
<author><name sortKey="Schloffel, Maria A" sort="Schloffel, Maria A" uniqKey="Schloffel M" first="Maria A" last="Schlöffel">Maria A. Schlöffel</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Salzer, Andrea" sort="Salzer, Andrea" uniqKey="Salzer A" first="Andrea" last="Salzer">Andrea Salzer</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wan, Wei Lin" sort="Wan, Wei Lin" uniqKey="Wan W" first="Wei-Lin" last="Wan">Wei-Lin Wan</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Wijk, Ringo" sort="Van Wijk, Ringo" uniqKey="Van Wijk R" first="Ringo" last="Van Wijk">Ringo Van Wijk</name>
<affiliation wicri:level="4"><nlm:affiliation>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam</wicri:regionArea>
<orgName type="university">Université d'Amsterdam</orgName>
<placeName><settlement type="city">Amsterdam</settlement>
<region>Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Del Corvo, Raffaele" sort="Del Corvo, Raffaele" uniqKey="Del Corvo R" first="Raffaele" last="Del Corvo">Raffaele Del Corvo</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Semanjski, Maja" sort="Semanjski, Maja" uniqKey="Semanjski M" first="Maja" last="Šemanjski">Maja Šemanjski</name>
<affiliation wicri:level="3"><nlm:affiliation>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Symeonidi, Efthymia" sort="Symeonidi, Efthymia" uniqKey="Symeonidi E" first="Efthymia" last="Symeonidi">Efthymia Symeonidi</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Slaby, Peter" sort="Slaby, Peter" uniqKey="Slaby P" first="Peter" last="Slaby">Peter Slaby</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kilian, Joachim" sort="Kilian, Joachim" uniqKey="Kilian J" first="Joachim" last="Kilian">Joachim Kilian</name>
<affiliation wicri:level="3"><nlm:affiliation>Analytics Unit, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Analytics Unit, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ma Ek, Boris" sort="Ma Ek, Boris" uniqKey="Ma Ek B" first="Boris" last="Ma Ek">Boris Ma Ek</name>
<affiliation wicri:level="3"><nlm:affiliation>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Munnik, Teun" sort="Munnik, Teun" uniqKey="Munnik T" first="Teun" last="Munnik">Teun Munnik</name>
<affiliation wicri:level="4"><nlm:affiliation>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam</wicri:regionArea>
<orgName type="university">Université d'Amsterdam</orgName>
<placeName><settlement type="city">Amsterdam</settlement>
<region>Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gust, Andrea A" sort="Gust, Andrea A" uniqKey="Gust A" first="Andrea A" last="Gust">Andrea A. Gust</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany andrea.gust@zmbp.uni-tuebingen.de.</nlm:affiliation>
<country wicri:rule="url">Allemagne</country>
<wicri:regionArea>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Plant physiology</title>
<idno type="eISSN">1532-2548</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Plants have evolved effective strategies to defend themselves against pathogen invasion. Starting from the plasma membrane with the recognition of microbe-associated molecular patterns (MAMPs) via pattern recognition receptors, internal cellular signaling pathways are induced to ultimately fend off the attack. Phospholipase D (PLD) hydrolyzes membrane phospholipids to produce phosphatidic acid (PA), which has been proposed to play a second messenger role in immunity. The Arabidopsis (<i>Arabidopsis thaliana</i>
) PLD family consists of 12 members, and for some of these, a specific function in resistance toward a subset of pathogens has been shown. We demonstrate here that Arabidopsis PLDγ1, but not its close homologs PLDγ2 and PLDγ3, is specifically involved in plant immunity. Genetic inactivation of <i>PLDγ1</i>
 resulted in increased resistance toward the virulent bacterium <i>Pseudomonas syringae</i>
 pv. <i>tomato</i>
 DC3000 and the necrotrophic fungus <i>Botrytis cinerea</i>
 As <i>pldγ1</i>
 mutant plants responded with elevated levels of reactive oxygen species to MAMP treatment, a negative regulatory function for this PLD isoform is proposed. Importantly, PA levels in <i>pldγ1</i>
 mutants were not affected compared to stressed wild-type plants, suggesting that alterations in PA levels are not likely the cause for the enhanced immunity in the <i>pldγ1</i>
 line. Instead, the plasma-membrane-attached PLDγ1 protein colocalized and associated with the BAK1-INTERACTING RECEPTOR-LIKE KINASES BIR2 and BIR3, which are known negative regulators of pattern-triggered immunity. Moreover, complex formation of PLDγ1 and BIR2 was further promoted upon MAMP treatment. Hence, we propose that PLDγ1 acts as a negative regulator of plant immune responses in complex with immunity-related proteins BIR2 and BIR3.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">32152212</PMID>
<DateRevised><Year>2020</Year>
<Month>07</Month>
<Day>02</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-2548</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>183</Volume>
<Issue>1</Issue>
<PubDate><Year>2020</Year>
<Month>05</Month>
</PubDate>
</JournalIssue>
<Title>Plant physiology</Title>
<ISOAbbreviation>Plant Physiol</ISOAbbreviation>
</Journal>
<ArticleTitle>The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.</ArticleTitle>
<Pagination><MedlinePgn>371-384</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1104/pp.19.01292</ELocationID>
<Abstract><AbstractText>Plants have evolved effective strategies to defend themselves against pathogen invasion. Starting from the plasma membrane with the recognition of microbe-associated molecular patterns (MAMPs) via pattern recognition receptors, internal cellular signaling pathways are induced to ultimately fend off the attack. Phospholipase D (PLD) hydrolyzes membrane phospholipids to produce phosphatidic acid (PA), which has been proposed to play a second messenger role in immunity. The Arabidopsis (<i>Arabidopsis thaliana</i>
) PLD family consists of 12 members, and for some of these, a specific function in resistance toward a subset of pathogens has been shown. We demonstrate here that Arabidopsis PLDγ1, but not its close homologs PLDγ2 and PLDγ3, is specifically involved in plant immunity. Genetic inactivation of <i>PLDγ1</i>
 resulted in increased resistance toward the virulent bacterium <i>Pseudomonas syringae</i>
 pv. <i>tomato</i>
 DC3000 and the necrotrophic fungus <i>Botrytis cinerea</i>
 As <i>pldγ1</i>
 mutant plants responded with elevated levels of reactive oxygen species to MAMP treatment, a negative regulatory function for this PLD isoform is proposed. Importantly, PA levels in <i>pldγ1</i>
 mutants were not affected compared to stressed wild-type plants, suggesting that alterations in PA levels are not likely the cause for the enhanced immunity in the <i>pldγ1</i>
 line. Instead, the plasma-membrane-attached PLDγ1 protein colocalized and associated with the BAK1-INTERACTING RECEPTOR-LIKE KINASES BIR2 and BIR3, which are known negative regulators of pattern-triggered immunity. Moreover, complex formation of PLDγ1 and BIR2 was further promoted upon MAMP treatment. Hence, we propose that PLDγ1 acts as a negative regulator of plant immune responses in complex with immunity-related proteins BIR2 and BIR3.</AbstractText>
<CopyrightInformation>© 2020 American Society of Plant Biologists. All Rights Reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Schlöffel</LastName>
<ForeName>Maria A</ForeName>
<Initials>MA</Initials>
<Identifier Source="ORCID">0000-0001-6818-1395</Identifier>
<AffiliationInfo><Affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Salzer</LastName>
<ForeName>Andrea</ForeName>
<Initials>A</Initials>
<Identifier Source="ORCID">0000-0003-0724-8298</Identifier>
<AffiliationInfo><Affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wan</LastName>
<ForeName>Wei-Lin</ForeName>
<Initials>WL</Initials>
<AffiliationInfo><Affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>van Wijk</LastName>
<ForeName>Ringo</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Del Corvo</LastName>
<ForeName>Raffaele</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Šemanjski</LastName>
<ForeName>Maja</ForeName>
<Initials>M</Initials>
<Identifier Source="ORCID">0000-0001-5683-4993</Identifier>
<AffiliationInfo><Affiliation>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Symeonidi</LastName>
<ForeName>Efthymia</ForeName>
<Initials>E</Initials>
<Identifier Source="ORCID">0000-0002-4412-4596</Identifier>
<AffiliationInfo><Affiliation>Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Slaby</LastName>
<ForeName>Peter</ForeName>
<Initials>P</Initials>
<Identifier Source="ORCID">0000-0002-9665-2040</Identifier>
<AffiliationInfo><Affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kilian</LastName>
<ForeName>Joachim</ForeName>
<Initials>J</Initials>
<Identifier Source="ORCID">0000-0001-5711-3688</Identifier>
<AffiliationInfo><Affiliation>Analytics Unit, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Maček</LastName>
<ForeName>Boris</ForeName>
<Initials>B</Initials>
<Identifier Source="ORCID">0000-0002-1206-2458</Identifier>
<AffiliationInfo><Affiliation>Proteome Center Tübingen, University of Tübingen, 72076 Tübingen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Munnik</LastName>
<ForeName>Teun</ForeName>
<Initials>T</Initials>
<Identifier Source="ORCID">0000-0002-4919-4913</Identifier>
<AffiliationInfo><Affiliation>Swammerdam Institute for Life Sciences, Section Plant Cell Biology, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gust</LastName>
<ForeName>Andrea A</ForeName>
<Initials>AA</Initials>
<Identifier Source="ORCID">0000-0003-0466-2792</Identifier>
<AffiliationInfo><Affiliation>Department of Plant Biochemistry, Center for Plant Molecular Biology, University of Tübingen, 72076 Tübingen, Germany andrea.gust@zmbp.uni-tuebingen.de.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>03</Month>
<Day>09</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Plant Physiol</MedlineTA>
<NlmUniqueID>0401224</NlmUniqueID>
<ISSNLinking>0032-0889</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Plant Physiol. 2020 May;183(1):33-34</RefSource>
<PMID Version="1">32385184</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year>
<Month>10</Month>
<Day>22</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>02</Month>
<Day>20</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>3</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>3</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>3</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32152212</ArticleId>
<ArticleId IdType="pii">pp.19.01292</ArticleId>
<ArticleId IdType="doi">10.1104/pp.19.01292</ArticleId>
<ArticleId IdType="pmc">PMC7210654</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Int J Mol Sci. 2018 Oct 17;19(10):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30336563</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Methods Mol Biol. 2013;1009:219-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23681537</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2006 Feb;18(2):465-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16377758</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 1999 Apr;119(4):1371-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10198096</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bioinformatics. 2009 Aug 15;25(16):2078-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19505943</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Prog Lipid Res. 2006 May;45(3):250-78</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16574237</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Exp Bot. 2011 Apr;62(7):2349-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21430291</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Prog Lipid Res. 2018 Jul;71:43-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29842906</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2018 Feb;93(4):592-613</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29266555</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2017 Sep;29(9):2285-2303</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28842532</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12857-12862</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31182605</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bioinformatics. 2009 Jul 15;25(14):1754-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19451168</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Elife. 2017 Mar 06;6:</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28262094</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Phytopathol. 2011;49:317-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21663438</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Plant Microbe Interact. 2012 Apr;25(4):471-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22204645</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Plant Microbe Interact. 2002 Aug;15(8):808-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12182338</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2003 Nov;15(11):2666-79</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14508002</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell. 2000 Jun;5(6):1003-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10911994</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2001 Aug;126(4):1449-58</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11500544</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Plant Sci. 2019 Jan 18;9:1991</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30713545</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Prog Lipid Res. 2016 Apr;62:55-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26783886</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Dev Cell. 2018 May 21;45(4):465-480.e11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29754803</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 1998 Dec;16(6):735-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10069079</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Plant Sci. 2019 Mar 18;10:275</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30936884</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>New Phytol. 2013 Jul;199(1):228-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23577648</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Biol. 2001 Jan;21(2):595-602</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11134345</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Plant Biol. 2009;60:379-406</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19400727</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Biochem Biophys. 1998 May 1;353(1):131-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9578608</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1997 Nov 7;272(45):28267-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9353280</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2002 Aug;129(4):1892-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12177503</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Bioinformatics. 2014 Jun 12;15:182</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24925680</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell Proteomics. 2012 Apr;11(4):M111.014555</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22215637</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell Physiol. 2009 Jan;50(1):78-89</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19017627</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2002 Mar;128(3):1057-68</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11891260</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2010 May;62(3):494-507</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20149133</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochim Biophys Acta. 2009 Sep;1791(9):869-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19394438</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2006 Sep 8;126(5):969-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16959575</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Plant Biol. 2017 Dec;40:82-88</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28865975</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2010 Jul;153(3):1098-111</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20488890</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>New Phytol. 2019 Mar;221(4):2080-2095</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30252144</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2008 Mar;20(3):803-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18364466</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2017 Jan 23;12(1):e0169905</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28114413</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Microbiol. 2011 Feb;14(1):54-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21215683</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Plant Biol. 2002 Aug;5(4):332-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12179967</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2006 Sep;47(6):947-59</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16925603</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2010 Jun 18;285(25):19035-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20410299</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2013 Oct;163(2):896-906</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23979971</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Methods Mol Biol. 2013;1009:3-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23681518</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Plant Biol. 2004 Jun;7(3):329-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15134755</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12217-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17626179</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2019 Dec;31(12):3015-3032</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31597687</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2003 May;132(1):311-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12746536</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Plant Biol. 2013;64:501-29</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23638827</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochim Biophys Acta. 2009 Sep;1791(9):845-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19540357</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Plant Sci. 2005 Mar;10(3):103-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15749466</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Sci STKE. 2001 Dec 04;2001(111):pe42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11734658</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2009 Jul 23;6(1):34-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19616764</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2009 May;58(3):376-87</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19143999</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2006 May 19;125(4):749-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16713565</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1978 Jul;75(7):3317-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">356052</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Plant. 2015 Apr;8(4):521-39</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25744358</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2001 May;26(3):237-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11446372</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2013 Nov 1;342(6158):624-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24114786</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Plant Sci. 2014 Nov 13;5:639</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25431578</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nanoscale. 2015 Feb 14;7(6):2511-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25569174</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Immunol. 2016 Sep;16(9):537-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27477127</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biosci Bioeng. 2007 Jul;104(1):34-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17697981</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Plant Biol. 2006 Oct;9(5):515-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16877031</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Methods. 2001 Dec;25(4):402-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11846609</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Plant Sci. 2019 Apr 05;10:362</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31024579</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Biochem Biophys. 2003 Apr 15;412(2):231-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12667487</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 1998 Mar;116(3):1163-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9501149</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2009 Aug;21(8):2357-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19690149</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Biol. 2014 Jan 20;24(2):134-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24388849</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Cell Dev Biol. 2012;28:489-521</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22559264</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Plant Sci. 2001 May;6(5):227-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11335176</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>New Phytol. 2010 Nov;188(3):762-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20796215</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2004 Apr 15;428(6984):764-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15085136</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Prog Lipid Res. 2019 Jan;73:1-27</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30465788</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Phytopathol. 2017 Aug 4;55:109-137</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28525309</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2007 Jul 26;448(7152):497-500</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17625569</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2004 Jul;39(1):1-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15200638</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2006 Apr 14;312(5771):264-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16614222</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2000 Aug;123(4):1507-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10938366</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2006 Feb;45(3):358-68</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16412083</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genes Dev. 2006 Mar 1;20(5):537-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16510871</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Brief Bioinform. 2013 Mar;14(2):178-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22517427</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Exp Bot. 2015 Apr;66(7):1721-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25680793</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2019 Aug;180(4):2004-2021</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31118265</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2018 Jul 11;24(1):168-179.e4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30001519</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2014 Jan;77(2):222-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24245741</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Allemagne</li>
<li>Pays-Bas</li>
</country>
<region><li>Bade-Wurtemberg</li>
<li>District de Tübingen</li>
<li>Hollande-Septentrionale</li>
</region>
<settlement><li>Amsterdam</li>
<li>Tübingen</li>
</settlement>
<orgName><li>Université d'Amsterdam</li>
</orgName>
</list>
<tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Schloffel, Maria A" sort="Schloffel, Maria A" uniqKey="Schloffel M" first="Maria A" last="Schlöffel">Maria A. Schlöffel</name>
</region>
<name sortKey="Del Corvo, Raffaele" sort="Del Corvo, Raffaele" uniqKey="Del Corvo R" first="Raffaele" last="Del Corvo">Raffaele Del Corvo</name>
<name sortKey="Gust, Andrea A" sort="Gust, Andrea A" uniqKey="Gust A" first="Andrea A" last="Gust">Andrea A. Gust</name>
<name sortKey="Kilian, Joachim" sort="Kilian, Joachim" uniqKey="Kilian J" first="Joachim" last="Kilian">Joachim Kilian</name>
<name sortKey="Ma Ek, Boris" sort="Ma Ek, Boris" uniqKey="Ma Ek B" first="Boris" last="Ma Ek">Boris Ma Ek</name>
<name sortKey="Salzer, Andrea" sort="Salzer, Andrea" uniqKey="Salzer A" first="Andrea" last="Salzer">Andrea Salzer</name>
<name sortKey="Semanjski, Maja" sort="Semanjski, Maja" uniqKey="Semanjski M" first="Maja" last="Šemanjski">Maja Šemanjski</name>
<name sortKey="Slaby, Peter" sort="Slaby, Peter" uniqKey="Slaby P" first="Peter" last="Slaby">Peter Slaby</name>
<name sortKey="Symeonidi, Efthymia" sort="Symeonidi, Efthymia" uniqKey="Symeonidi E" first="Efthymia" last="Symeonidi">Efthymia Symeonidi</name>
<name sortKey="Wan, Wei Lin" sort="Wan, Wei Lin" uniqKey="Wan W" first="Wei-Lin" last="Wan">Wei-Lin Wan</name>
</country>
<country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Van Wijk, Ringo" sort="Van Wijk, Ringo" uniqKey="Van Wijk R" first="Ringo" last="Van Wijk">Ringo Van Wijk</name>
</region>
<name sortKey="Munnik, Teun" sort="Munnik, Teun" uniqKey="Munnik T" first="Teun" last="Munnik">Teun Munnik</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PlantImRecepV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000037 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000037 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Bois
   |area=    PlantImRecepV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:32152212
   |texte=   The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:32152212" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a PlantImRecepV1

This area was generated with Dilib version V0.6.38.
Data generation: Sat Nov 21 12:33:18 2020. Site generation: Sat Nov 21 12:33:47 2020

	Serveur d'exploration sur les récepteurs immunitaires végétaux
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les récepteurs immunitaires végétaux

The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.

The BIR2/BIR3-Associated Phospholipase Dγ1 Negatively Regulates Plant Immunity.

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki